Gregory House MD is in this clip from season five haunted by the spirit of Amber, or as House used to call her, "Cutthroat Bitch", for whose death he correctly feels responsible. Years of Vicadin abuse has caught up with him, and he is currently a kinder, gentler House. Prior to his detoxing, however, things came to a head when his subconscious feelings of guilt, longing, and Gods know what other emotions manifested in the form of the girl whose death he caused, a former colleague and fiance' of his best friend, Wilson.
And so it goes. Our most important relationships live on in our subconscious minds long after the people themselves have left this mortal vale, or at least our lives. They don't usually manifest in such an extremely profound manner as this, but they can, and with very malefic consequences to our psyches, especially when they are manifestations of our most base emotions brought about by heavy drug use. In them we can see our shame, our guilt, our lusts, our hatreds, and our most dreaded fears.
When she first appeared to House, it did not take long for her, this subconscious manifestation of House's most selfish inclinations, to lead him into commiting the attempted murder of another colleague, Chase. He realized then what an unhealthy relationship he had been toying with. Unfortunately, as seen here, this was one ghost who was not going to away easily into that good night.
